The spatial distribution of social and economic indicators for populations such as households or businesses represents an important tool to design samples and its use is increased in the last decades as GIS and GPS technologies made cheaper to add information regarding the exact or estimated position for each record in the sampling frame. Indeed, it is a common practice within National Statistical Offices to add the available data on the spatial characteristics of each entity to the sampling frames used for social and economic surveys. In this lesson, the characteristics and statistical properties of different strategies for spatially balanced sampling are presented and compared.